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Can you take anti inflammatories with methotrexate? Concerns. There have been a number of cases of methotrexate toxicity — some fatal — reported in patients taking non-steroidal anti - inflammatory drugs, such as ibuprofen, with methotrexate. However, some studies have found that NSAIDs do not change the pharmacokinetics of methotrexate.
Can you stop sulfasalazine suddenly? It is safe to just stop sulfasalazine ; you do not need to slowly reduce the dose. However, keep in mind, if you were gaining any benefit, it will usually take at least 6 weeks to lose it.
