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What causes spondylitis? Ankylosing spondylitis is a form of arthritis that primarily affects your spine. It causes severe inflammation of the vertebrae that might eventually lead to chronic pain and disability. In more advanced cases, the inflammation can cause new bone to form on the spine. This may lead to deformity.
What does it mean if you are HLA b27 positive? A negative result mean you don't have HLA - B27 in your blood. A positive result means HLA - B27 was found in your blood. You may have a higher-than- average risk of certain autoimmune diseases, such as ankylosing spondylitis and reactive arthritis. If it's a common HLA genotype, the child could have many potential fathers.
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