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Is it safe to use Apetamin? Apetamin : An Unapproved Drug Masquerading as a Vitamin Syrup for Weight Gain. But Apetamin is not a harmless vitamin supplement as payment facilitators might think — it's a drug that has not been approved for use in many countries, and its sale in the US can lead to BRAM and GBPP fines. Is cyproheptadine safe for weight gain? It has long been known that the administration of antihistamines can cause weight gain. In fact, one antihistamine, cyproheptadine, has been used for this purpose. One reason, which may be the most reasonable, is that histamine is known to reduce the appetite, and antihistamines, therefore, counteract this effect.
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