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Do antidepressants help with mood swings? Antidepressants work by balancing chemicals in your brain called neurotransmitters that affect mood and emotions. These depression medicines can help improve your mood, help you sleep better, and increase your appetite and concentration. Is HRT necessary? HRT is taken for the correct reasons, i.e. to alleviate the symptoms of the menopause. It has a role in the prevention of osteoporosis but long term use is often required. HRT is taken for only as long as necessary at the lowest effective dose. HRT users are assessed by their GP at least once a year.
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